April 30, 2024

Unveiling the Dynamics of Complement Activation in Dialysis: Insights from Invizius

In this Editorial Article, experts Dr. Andy Herbert, Co-Founder and CTO, and Dr. Elizabeth Blackburn, Principal Scientist at Invizius, share how their research contributes to tackling biocompatibility challenges in extracorporeal systems and how immunoassays play a critical role in generating reproducible and robust data.

Regulatory bodies worldwide increasingly recognize the importance of complement measurement in ensuring the safety and efficacy of medical devices. 

April 30, 2024

Unveiling the Dynamics of Complement Activation in Dialysis: Insights from Invizius

In this Editorial Article, experts Dr. Andy Herbert, Co-Founder and CTO, and Dr. Elizabeth Blackburn, Principal Scientist at Invizius, share how their research contributes to tackling biocompatibility challenges in extracorporeal systems and how immunoassays play a critical role in generating reproducible and robust data.

Regulatory bodies worldwide increasingly recognize the importance of complement measurement in ensuring the safety and efficacy of medical devices. 

During extracorporeal treatments such as dialysis, the interaction between the patient's bloodstream and foreign surfaces can trigger immune responses in most individuals. Despite significant advances in materials science aimed at reducing complications, patients undergoing extracorporeal treatments are still exposed to foreign materials for prolonged periods. If not regulated, these responses can lead to complications such as inflammation, thrombosis, or tissue damage, resulting in poor patient prognosis. Chronic inflammation is a well-known risk factor for Cardiovascular disease (CVD), which is the most common cause of death in hemodialysis (HD) patients.

Download this exclusive interview to learn more about the importance of assessing complement response in extracorporeal systems and how Invizius' work has the potential to significantly benefit patients undergoing all forms of hemodialysis.

 

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