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The hormone fibroblast growth factor 21 (FGF21) holds considerable promise as a therapeutic mechanism and understanding the physiology and the pharmacology of FGF21 is key to all drug development projects related to this field. In this performance data file, we present data for the FGF21 cell line ... Read more
Immunogenic responses, where antibodies are produced by the immune system as a protective response, can adversely affect the pharmacokinetics, bioavailability, and efficacy of biopharmaceuticals, and may even neutralize the activity of the drug. Many different factors influence the immunogenicity ... Read more
Tune in to this webinar to learn how reporter-gene assays, in combination with complement system assays, can be used to determine drug mechanisms of action and the expected immune response. In this webinar, Therese Segerstein and Ali Qamar, explain how functional assays can be used in safe and ... Read more
This scientific talk, presented at PEGS 2021, presents a highly sensitive iLite® reporter assay, providing a highly sensitive, rapid, precise method for quantifying NAb response to a wide range of recombinant AAV vectors. A highly sensitive iLite® reporter assay based on a packaging cell line ... Read more