iLite® VEGF Assay Ready Cells
BM4021
The iLite® VEGF assay quantifies vascular endothelial growth factor activity with high sensitivity. A valuable tool for assessing angiogenesis modulation in oncology and ophthalmology research.
- High sensitivity and large dynamic range
- "Assay-ready" format for rapid and convenient use
- Reproducible and biologically relevant results
- Reduced assay variability and higher reproducibility compared to cells in culture
Product Overview
iLite® VEGF Assay Ready Cells are human embryonic kidney cells (HEK-293*). They have been genetically engineered and optimized to respond to VEGF with specific, proportional expression of Firefly Luciferase.
iLite® VEGF Assay Ready Cells measure the functional activity of VEGF, the potency VEGF inhibitors, and can also be used to detect neutralizing antibodies against inhibitor drugs in human serum. These cells are not dependent on the structure of the drug, therefore, different anti-VEGF drugs can be measured in the same assay.
iLite VEGF Assay Ready Cells are well suited for direct comparisons of biosimilars and innovator drugs in the same assay, making them an excellent tool for biosimilar development.
* The HEK-293 cell line has been used under a license obtained from AdVec Inc.
FOR RESEARCH USE ONLY
How it works
The function of iLite assays
iLite cells have receptors on the cell surface that can bind to the marker under study.
What's in the box?
>250µl of Assay Ready Cells suspended in cryoprotective medium.
Specifications
| Product code | BM4021 |
| Assay target | VEGF |
| Size | 1 vial corresponding to one 96 well plate |
| Technology | Cell-based reporter gene assay |
| Detection system | Luminescence |
| Regulatory status | Research Use Only |
Documents
Application Note
