The iLite® VEGF Assay Ready Cells have been genetically engineered to specifically measure the activity of VEGF, the potency VEGF inhibitors, and can also be used to detect neutralizing antibodies against inhibitor drugs in human serum.
iLite VEGF assay ready cells measures the functional activity of VEGF and is not dependent on the structure of the drug, therefore, different anti-VEGF drugs can be measured in the same assay.
The assay ready iLite VEGF cells is a human embryonic kidney cell line (HEK-293*; ATCC #CRL-1573) that have been genetically engineered and optimized to respond to VEGF with specific, proportional expression of Firefly Luciferase.
iLite VEGF Assay Ready Cells are well suited for direct comparisons of biosimilars and innovator drugs in the same assay, making them an excellent tool for biosimilar development.
* The HEK-293 cell line has been used under a license obtained from AdVec Inc.
FOR RESEARCH USE ONLY
|Size||1 vial corresponding to one 96 well plate|
|Read-out of results||Quantitative,|
|Regulatory status||Research Use Only|
>250µl of Assay Ready Cells suspended in cryoprotective medium from Amsbio (Cat. No 11888).
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