Complement C4d - RUO
COMPL C4d RUO
Detect complement activation via the classical and lectin pathways with this C4d biomarker sandwich ELISA — ideal for assessing complement dysregulation in autoimmune and transplant-related research.
- Reliable, objective, and easy-to-interpret results
- Results in just a few hours
- Low inter-assay variability and excellent reproducibility
- Developed by our in-house experts in collaboration with key opinion leaders
- Ready-to-use reagents for a streamlined workflow
- Excellent specificity means precise results without false positives
Product Overview
The Complement C4d assay is a highly specific ELISA kit for measurement of C4d in human plasma. The assay targets a unique cleavage epitope found on C4d, allowing to measure the C4d fragment specifically.
C4d is a product of the classical and the lectin pathways. It is increasingly recognized as a potential biomarker for diseases where antibodies can cause tissue damage, such as systemic autoimmune diseases.
C4d has the potential to detect patients at risk of developing tissue damage from antibody-mediated diseases. It is also used during the development of new therapeutics that block complement activation to identify patients who may benefit from these drugs.
For custom requests, please contact an expert.
FOR RESEARCH USE ONLY
What's in the box?
- One frame with micro titer wells (12x8)
- 1,5mL Low control
- 1,5mL High control
- 2x30 mL Diluent
- 15 mL Conjugate
- 15 mL Substrate TMB
- 15 mL Stop solution
- 30 mL Wash solution, 30x concentrated
- 6 x 1,5mL vials with calibrators containing human recombinant C4d - 0 ng/mL, 5ng/mL, 25 ng/mL, 100ng/mL, 200ng/mL and 400ng/mL
Please note: All reagents in the kit are ready to use except the wash solution. The reagents should be stored at 2-8°C. Components from different lots shall not be mixed. When stored at 2-8°C the diluted wash solution is stable until the date of expiration of the kit.
Specifications
| Product code | COMPL C4d RUO |
| Assay target | C4d |
| Size | 96 wells |
| Technology | ELISA |
| Detection system | HRP/TMB read at 450 nm |
| Regulatory status | Research Use Only |
| Range | 0-400 ng/ml |
| Assay time | 2h |
Documents
Downloads
Novel COVID-19 Biomarkers: The role of complement C4d
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Complement System Specialist Review
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Unraveling Complement’s Role in Blindness: The Work of Professor Simon Clark
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Insights on Targeting Complement Dysregulation - Dr. Elena Goicoechea de Jorge
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20 Years of Innovation: The Legacy of the WIESLAB® Complement System Assays
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Meet the 2025 Svar Complement Excellence Award Recipients
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Insights from Two Complement Excellence Award Recipients
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Get a Free Complement System Poster
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Complement Components as Prognostic Biomarkers in Renal Cancer
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Roundtable: Challenges & Solutions in Next-Gen Complement Therapeutics
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The Complement System Provides Promise of Novel Prognostic Biomarkers for Cancer
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The Complement System in Infectious Disease: Expert Opinion on Future Diagnostic and Therapeutic Pot...
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Exploring Existing Human Complement C4d, TCC & Functional Activity Assays
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A Guide to Complement Therapeutics for Drug Development Professionals
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