Complement TCC - RUO

COMPL TCC RUO

Measure the formation of the terminal complement complex (TCC/sC5b-9) to evaluate full pathway activation and membrane attack complex formation. TCC measurement is essential for monitoring complement activation in inflammation, oncology, and immune-mediated diseases.

  • Reliable, objective, and easy-to-interpret results
  • Results in just a few hours
  • Low inter-assay variability and excellent reproducibility
  • Developed by our in-house experts in collaboration with key opinion leaders
  • Ready-to-use reagents for a streamlined workflow
  • Excellent specificity means precise results without false positives
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Complement TCC - RUO

Product Overview

The Complement TCC is a flexible and easy to use immunoassay for determination of the terminal complement complex (TCC, also known as sC5b-9). The assay is well adapted for assessment of complement activation in applications spanning in vivo and in vitro complement activation and inhibition studies.

Complement TCC is an excellent marker for complement studies in basic and translational research, clinical study, and safety studies of medical devices and drugs..

TCC is also well suited for studies of complement activation during the development of pharmaceuticals and medical devices (biological safety testing). Measurement of TCC is part of the recommended tests for assessing complement activation according to ISO standard 10993-4 for hemocompatibility testing.

For custom requests, please contact an expert.

FOR RESEARCH USE ONLY

What's in the box?

  • One frame with microtiter wells (12x8)
  • 1.5mL Low control
  • 1.5mL High control
  • 2 x 30 mL Diluent
  • 15 mL Conjugate
  • 15 mL Substrate TMB
  • 15 mL Stop solution
  • 30 mL Wash solution, 30x concentrated
  • 6 x 1.5mL vials with calibrators containing human purified TCC - 0 ng/mL, 10ng/mL, 50 ng/mL, 100ng/mL, 200ng/mL and 400ng/mL.

Please note: All reagents in the kit are ready to use except the wash solution. The reagents should be stored at 2- 8°C. Components from different lots shall not be mixed.

Specifications

Product code COMPL TCC RUO
Assay target TCC
Size 96 wells
Technology ELISA
Detection system HRP/TMB read at 450 nm
Regulatory status Research Use Only
Range 0-400 ng/ml
Assay time 2h

Documents

IFU

Instructions for Use

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Product Flyer

Product Flyer

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SDS

Safety Data Sheet

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