INDIVIDUAL TEST 031
Ribosomal P-Protein (Ribo-P) Antibodies
Indication
Suspicion of systemic lupus erythematosus, especially with CNS involvement
Sample material
Serum
- Minim. volume: 0,5 mL
Transport
- Within Sweden: room temperature
- International: cold
Method
ELISA-based technique (EliA)
Reference interval
<7 U/mL negative, 7- <10 U/mL borderline
Result
Results are reported as negative, borderline, or positive with a concentration (U/mL).
Interpretation
Antibodies against Ribosomal P-protein are associated with neuropsychiatric manifestations in systemic lupus erythematosus (SLE).
References
- Fritzler MJ et al. J Rheumatol. 2018. The Antinuclear Antibody Test in the Diagnosis of Antisynthetase Syndrome and Other Autoimmune Myopathies. PMID: 29496922
- Pagkopoulou E et al. J Clin Med. 2025. Autoantibodies in Systemic Lupus Erythematosus: Diagnostic and Pathogenic Insights. PMID: 40869539
- Kamstrupet S et al. Lupus Sci Med. 2025. Anti-ribosomal-P protein antibodies and systemic lupus erythematosus (SLE): in a cross-sectional study of Danish adult patients with SLE, no significant association is found between anti-ribosomal-P and neuropsychiatric SLE. PMID: 40819906
Last updated: 2025-11-21
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ENSKILD ANALYS 031
Ribosomalt P-protein (Ribo-P)-antikroppar
Indikation
Misstanke om systemisk lupus erytematosus, särskilt vid CNS engagemang
Provmaterial
Serum
- Minim. volym: 0,5 mL
Transport
- Inom Sverige: rumstemperatur
- Internationellt: kylt
Metod
ELISA-baserad teknik (EliA)
Referensintervall
<7 U/mL negativt, 7- <10 U/mL gränsvärde
Resultat
Resultatet anges som negativt, gränsvärde eller positivt med koncentration (U/mL).
Tolkning
Antikroppar mot ribosomalt P-protein är associerade med neuropsykiatriska manifestationer vid systemisk lupus erythematosus (SLE).
Referenser
- Fritzler MJ et al. J Rheumatol. 2018. The Antinuclear Antibody Test in the Diagnosis of Antisynthetase Syndrome and Other Autoimmune Myopathies. PMID: 29496922
- Pagkopoulou E et al. J Clin Med. 2025. Autoantibodies in Systemic Lupus Erythematosus: Diagnostic and Pathogenic Insights. PMID: 40869539
- Kamstrupet S et al. Lupus Sci Med. 2025. Anti-ribosomal-P protein antibodies and systemic lupus erythematosus (SLE): in a cross-sectional study of Danish adult patients with SLE, no significant association is found between anti-ribosomal-P and neuropsychiatric SLE. PMID: 40819906
Senast uppdaterat: 2025-11-21