INDIVIDUAL TEST 052
Dopamin-2 Receptor Antibodies (IgG)
Indication
Suspicion of autoimmune encephalitis
Sample material
Serum
- Minim. volume: 0,5 mL
CSF
- Minim. volume: 0,5 mL
Transport
- Within Sweden: room temperature
- International: cold
Method
Cell-based assay (CBA), indirect immunofluorescence (IIF)
Reference interval
Serum: <1:10 negative
CSF: negative
Result
Results are reported as negative or positive. A positive result is followed by a titer (serum).
Interpretation
Antibodies against D2R have been reported in isolated cases of autoimmune encephalitis in children.
References
- Cellucci T et al. Neurol Neuroimmunol Neuroinflamm 2020. Clinical approach to the diagnosis of autoimmune encephalitis in the pediatric patient. PMID: 31953309
- Liu Y et al. Neurol Neuroimmunol Neuroinflamm. 2022. Relapsing and Immune-Responsive Paroxysmal Jaw Clonus With Blepharospasm and Sialorrhea Associated With D2R Autoantibodies. PMID: 35459715
- Gövert F et al. 2020. Neurol Res Pract. Antibody-related movement disorders - a comprehensive review of phenotype-autoantibody correlations and a guide to testing. PMID: 33324912
Last updated: 2025-12-05
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ENSKILD ANALYS 052
Dopamin-2 receptor-antikroppar (IgG)
Provmaterial
Serum
- Minim. volym: 0,5 mL
Likvor
- Minim. volym: 0,5 mL
Transport
- Inom Sverige: rumstemperatur
- Internationellt: kylt
Metod
Cell-based assay (CBA), indirekt immunofluorescens (IIF)
Referensintervall
Serum: <1:10 negativt
Likvor: negativt
Resultat
Resultat anges som negativt eller positivt. Positivt resultat titreras (serum).
Tolkning
Antikroppar mot D2R har rapporterats i enstaka fall med autoimmun encefalit hos barn.
Referenser
- Cellucci T et al. Neurol Neuroimmunol Neuroinflamm 2020. Clinical approach to the diagnosis of autoimmune encephalitis in the pediatric patient. PMID: 31953309
- Liu Y et al. Neurol Neuroimmunol Neuroinflamm. 2022. Relapsing and Immune-Responsive Paroxysmal Jaw Clonus With Blepharospasm and Sialorrhea Associated With D2R Autoantibodies. PMID: 35459715
- Gövert F et al. 2020. Neurol Res Pract. Antibody-related movement disorders - a comprehensive review of phenotype-autoantibody correlations and a guide to testing. PMID: 33324912
Senast uppdaterat: 2025-12-05