INDIVIDUAL TEST 085
Striational Antibodies
Indication
Suspicion of Myasthenia Gravis (MG) and thymoma
Sample material
Serum
- Minim. volume: 0,5 mL
Transport
- Within Sweden: room temperature
- International: cold
Method
Indirect immunofluorescence (IIF)
Reference interval
<1/20 negative
Result
Results are reported as negative or positive with fluorescence intensity.
Interpretation
Antibodies against striated muscle can be specific for Titin which is associated with late onset Myasthenia Gravis (MG).
References
- Romi F et al. J Neurol. 2000. Muscle autoantibodies in subgroups of myasthenia gravis patients. PMID: 10896269
- Loser V et al. Front Neurol. 2024. Autoantibodies in neuromuscular disorders: a review of their utility in clinical practice. PMID: 39555481
Last updated: 2025-10-09
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ENSKILD ANALYS 085
Tvärstrimmig muskel-antikroppar
Indikation
Misstanke om myastenia gravis (MG) och thymom
Provmaterial
Serum
- Minim. volym: 0,5 mL
Transport
- Inom Sverige: rumstemperatur
- Internationellt: kylt
Metod
Indirekt immunofluorescens (IIF)
Referensintervall
<1/20 negativt
Resultat
Resultat anges som negativt eller positivt med fluorescensens styrka.
Tolkning
Antikroppar mot tvärstrimmig muskel kan vara uttryck för antikroppar mot Titin vilket är associerat med late onset myastenia gravis (MG), men även med tymom.
Referenser
- Romi F et al. J Neurol. 2000. Muscle autoantibodies in subgroups of myasthenia gravis patients. PMID: 10896269
- Loser V et al. Front Neurol. 2024. Autoantibodies in neuromuscular disorders: a review of their utility in clinical practice. PMID: 39555481
Senast uppdaterat: 2025-10-09
Mer information
Detta är en ackrediterad analys.> Läs mer [.pdf]
Mer information om provtagning.
> Läs mer