INDIVIDUAL TEST 113
ZnT8 Antibodies
Indication
Suspicion of type 1 diabetes (T1D).
Method
Radio immunoprecipitation (RIA).
Result
Negative, borderline, or positive with a ratio.
Interpretation
Antibodies against ZnT8 is an independent marker for type 1 diabetes (T1D) and combined with antibodies against GAD-65, insulin, IA-2 and islet cells it gives an improved diagnostic sensitivity. Anti-ZnT8 antibodies can be associated with different clinical phenotypes of T1D compared to anti-GAD-65 or anti-IA-2 antibodies.
Reference
- Han et. al. Am J Transl Res. 2013. PMID: 23724162
Last updated: 2024-07-02
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ENSKILD ANALYS 113
ZnT8-antikroppar
Indikation
Misstanke om type 1 diabetes (T1D).
Method
Radioimmunoprecipitering (RIA).
Resultat
Negativt, gränsvärde eller positivt med kvot.
Tolkning
Antikroppar mot ZnT8 är en oberoende markör för diabetes typ 1 (T1D) och kombineras med antikroppar mot GAD-65, Insulin, IA-2 och ö-celler för att ge en förbättrad diagnostisk sensitivitet. Anti-ZnT8 kan associeras med olika kliniska fenotyper än anti-GAD-65 eller anti-IA-2.
Referenser
- Han et. al. Am J Transl Res. 2013. PMID: 23724162
Senast uppdaterat: 2024-07-02