DIAGNOSTIC TEST 260, 282
Bullous Pemphigoid (BP180/BP230) Antibodies (IgG)
Diagnostic test for antibodies against BP180 (IgG) and BP230 (IgG). For suspicion of autoimmune skin diseases such as pemphigoid and differential diagnosis of pemphigus, EBA etc.
Indication
Suspicion of Bollous pemphigoid and differential diagnosis of pemphigus and EBA
Sample material
Serum
- Minim. volume: 0,5 mL
Transport
- Within Sweden: room temperature
- International: cold
Method
ELISA
Reference interval
<1.0 negative
Result
Results are reported as negative or positive with a ratio.
Interpretation
Antibodies against BP180 occurs in almost all patients with Bullous pemphigoid (BP). The level of antibodies correlates with disease activity. Antibodies may be associated with paraneoplastic pemphigoid and different variants of BP (Pemphigoid gestationis, Cicatricial pemphigoid).
Antibodies against Dystonin occur in Bullous pemphigoid (BP). The antibodies are directed against the basement membrane and are present in approximately 65% of patients with BP.
References
- Koga H et al. J Dermatol. 2025. Correlation of BP180, BP230, and type VII collagen antibody titers in serum, blister fluid, erosion, and saliva in pemphigoid diseases. PMID: 39916594
- Minakawa S et al. Acta Dermatovenerol Croat. 2022. A Case of Anti-BP180-type Mucous Membrane Pemphigoid with IgG and IgA Autoantibodies Showing Distinct Reactivities. PMID: 36153720
Included in these panels
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How to order
This test is only available as part of a test panel.
Last updated: 2026-09-14
