INDIVIDUAL TEST 260, 282
Bullous Pemphigoid (BP180/BP230) Antibodies (IgG)
Indication
Suspicion of Bollous pemphigoid and differential diagnosis of pemphigus and EBA
Sample material
Serum
- Minim. volume: 0,5 mL
Transport
- Within Sweden: room temperature
- International: cold
Method
ELISA
Reference interval
<1.0 negative
Result
Results are reported as negative or positive with a ratio.
Interpretation
Antibodies against BP180 occurs in almost all patients with Bullous pemphigoid (BP). The level of antibodies correlates with disease activity. Antibodies may be associated with paraneoplastic pemphigoid and different variants of BP (Pemphigoid gestationis, Cicatricial pemphigoid).
Antibodies against Dystonin occur in Bullous pemphigoid (BP). The antibodies are directed against the basement membrane and are present in approximately 65% of patients with BP.
References
- Koga H et al. J Dermatol. 2025. Correlation of BP180, BP230, and type VII collagen antibody titers in serum, blister fluid, erosion, and saliva in pemphigoid diseases. PMID: 39916594
- Minakawa S et al. Acta Dermatovenerol Croat. 2022. A Case of Anti-BP180-type Mucous Membrane Pemphigoid with IgG and IgA Autoantibodies Showing Distinct Reactivities. PMID: 36153720
Last updated: 2025-11-21
Can't find what you're looking for? We are here to help
ENSKILD ANALYS 260, 282
Bullös Pemfigoid (BP180/BP230) - antikroppar (IgG)
Indikation
Misstanke om Bullös pemfigoid och differentialdiagnostik mot pemfigus
Provmaterial
Serum
- Minim. volym: 0,5 mL
Transport
- Inom Sverige: rumstemperatur
- Internationellt: kylt
Metod
ELISA
Referensintervall
<1.0 negativt
Resultat
Resultat anges som negativt eller positivt med kvot.
Tolkning
Antikroppar mot BP180 förekommer hos nästan alla patienter med Bullous pemfigoid (BP). Nivån av antikropparna korrelerar med sjukdomsaktivitet. Antikropparna kan vara förknippade med paraneoplastisk pemfigoid och olika varianter av BP (Pemphigoid gestationis, Cicatricial pemphigoid).
Antikroppar mot Dystonin förekommer vid Bullous pemfigoid (BP). Antikropparna riktas mot basalmembranet och förekommer hos ca 65% av patienterna med BP.
Referenser
- Koga H et al. J Dermatol. 2025. Correlation of BP180, BP230, and type VII collagen antibody titers in serum, blister fluid, erosion, and saliva in pemphigoid diseases. PMID: 39916594
- Minakawa S et al. Acta Dermatovenerol Croat. 2022. A Case of Anti-BP180-type Mucous Membrane Pemphigoid with IgG and IgA Autoantibodies Showing Distinct Reactivities. PMID: 36153720
Senast uppdaterat: 2025-11-21