INDIVIDUAL TEST 780
21-Hydroxylase Antibodies
Indication
Suspicion of Addison’s disease
Sample material
Serum
- Minim. volume: 0,5 mL
Transport
- Within Sweden: room temperature
- International: cold
Method
Radioimmunoprecipitation (RIP)
Reference interval
<10 negative, 10-<15 borderline
Result
Results are reported as negative, borderline, or positive with a ratio.
Interpretation
Antibodies against Steroid 21-hydroxylase is a strong marker for autoimmune adrenal cortex insufficiency (Addison’s disease).
References
- Feyzullova A et al. J Clin Med. 2025. Prevalence of Various Systemic and Organ-Specific Autoimmune Markers in Addison's Disease Patients Compared to Healthy Controls. PMID: 40507712
- Wolff ASB et al. Front Endocrinol (Lausanne). 2023. Autoimmune primary adrenal insufficiency -current diagnostic approaches and future perspectives. PMID: 38027140
Last updated: 2025-11-21
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ENSKILD ANALYS 780
21-Hydroxylas-antikroppar
Indikation
Misstanke om Addisons sjukdom
Provmaterial
Serum
- Minim. volym: 0,5 mL
Transport
- Inom Sverige: rumstemperatur
- Internationellt: kylt
Metod
Radioimmunoprecipitation (RIP)
Referensintervall
< 10 negativt, 10-<15 gränsvärde
Resultat
Resultat anges som negativt, gränsvärde eller positivt med en kvot.
Tolkning
Antikroppar mot Steroid-21-Hydroxylas är en stark markör för autoimmun binjurebarksinsufficiens (Addisons sjukdom).
Referenser
- Feyzullova A et al. J Clin Med. 2025. Prevalence of Various Systemic and Organ-Specific Autoimmune Markers in Addison's Disease Patients Compared to Healthy Controls. PMID: 40507712
- Wolff ASB et al. Front Endocrinol (Lausanne). 2023. Autoimmune primary adrenal insufficiency -current diagnostic approaches and future perspectives. PMID: 38027140
Senast uppdaterat: 2025-11-21