Vial

INDIVIDUAL TEST 871

Neurochondrin antibodies

Indication

Autoimmune cerebellar ataxia

Method

Indirect immunofluorescence. The method is not yet validated.

Answer

Reported as negative or positive with titer.
Can be tested in serum and CSF.

Interpretation

Antibodies against Neurochondrin have been reported in cases with autoimmune cerebellar degeneration with rapidly progressive cerebellar ataxia. The antibodies are usually not associated with malignancy.

References

1. Miske R, et al. Neurochondrin is a neuronal target antigen in autoimmune cerebellar degeneration. Neurol Neuroimmunol Neuroinflamm. 2016 Dec 5;4(1):e307. PMID: 27957508
2. Shelly S, et al. Neurochondrin neurological autoimmunity. Neurol Neuroimmunol Neuroinflamm. 2019 Sep 11;6(6):e612. PMID: 31511329

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Vial

ENSKILD ANALYS 871

Neurochondrinantikroppar

Indikation

Autoimmun cerebellär ataxi

Metod

Indirekt immunofluorescens. Metoden är ännu inte validerad.

Svar

Anges som negativ eller positiv med titer.
Kan testas i serum och likvor.

Tolkning

Antikroppar mot neurochondrin har rapporterats vid autoimmun cerebellär degeneration med snabbt progredierande ataxi. De är vanligtvis inte associerade med malignitet.

Referenser

1. Miske R, et al. Neurochondrin is a neuronal target antigen in autoimmune cerebellar degeneration. Neurol Neuroimmunol Neuroinflamm. 2016 Dec 5;4(1):e307. PMID: 27957508
2. Shelly S, et al. Neurochondrin neurological autoimmunity. Neurol Neuroimmunol Neuroinflamm. 2019 Sep 11;6(6):e612. PMID: 31511329

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