INDIVIDUAL TEST 874
ANNA-3 Antibodies
Indication
Paraneoplastic neurological syndroms.
Method
Indirect immunofluorescence.
Result
The result is given as negative or positive with a titer.
Interpretation
ANNA-3 is a rare paraneoplastic marker which have been detected in patients with small cell lung cancer (SCLC) but have also been found in lung adenocarcinoma and esophagus. Clinical symptoms are sensory-motor neuropathy with or without ataxia, cerebellar ataxia, brain stem encephalomyopathy with sensitivity disorders. The antibodies may be present along with other paraneoplastic markers such anti-Ri (Nova 1/ ANNA-2) and calcium channel antibodies (VGCC).
Last updated: 2024-06-19
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ENSKILD ANALYS 874
ANNA-3-antikroppar
Indikation
Misstanke om paraneoplastiskt syndrom.
Metod
Indirekt immunofluorescens.
Resultat
Resultatet anges som negativt eller positivt med titer.
Tolkning
ANNA-3 är en sällsynt paranoplastisk markör som har detekterats hos patienter med lungcancer i lungcancer (SCLC), men har också hittats i lungadenetokarcinom och matstrupe. Kliniska symptom är sensorisk-motorisk neuropati med eller utan ataxi, cerebellär ataxi, hjärnstemencefalomyopati med känslighetsstörningar. Antikropparna kan vara närvarande tillsammans med andra paraneoplastiska markörer sådana anti-Ri (Nova 1 / ANNA-2) och kalciumkanalantikroppar (VGCC).
Senast uppdaterat: 2024-06-19