Svar Life Science

Online Presentation

Complement Components as Prognostic Biomarkers in Renal Cancer

Complement C1s and C4d as Prognostic Biomarkers in Renal Cancer: Emergence of Non-canonical Functions of C1s

Join us in this presentation to learn about the role of the complement system in renal cancer.


Duration: ~17 minutes 

Speaker: M. Revel, M. A. Dragon-Durey and L.T. Roumenina from Cordeliers Research Center INSERM, Paris.

Online Presentation

Complement Components as Prognostic Biomarkers in Renal Cancer

Complement C1s and C4d as Prognostic Biomarkers in Renal Cancer: Emergence of Non-canonical Functions of C1s

Join us in this presentation to learn about the role of the complement system in renal cancer.


Duration: ~17 minutes 

Speaker: M. Revel, M. A. Dragon-Durey and L.T. Roumenina from Cordeliers Research Center INSERM, Paris.

Join this presentation to watch Dr. Lubka Roumenina and her colleagues present their latest finding on the role of the complement system in renal cancer. They have recently published a paper in Cancer Immunology Research where they found that complement activation, as reflected by high plasma C4d or as C4d deposits at the tumor site, was associated with poor prognosis in patients suffering from renal cell carcinoma.

They also found that C1s, a C4-activating enzyme, plays a dual role in promoting ccRCC progression by triggering complement activation in a noncanonical manner.

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