Performance Data

iLite® C5a Performance Data

The iLite C5a cells can be used for the quantification of C5a activity, and for the determination of inhibitory activity against either C5a itself or against the C5a receptor in test samples, including human serum.

In this performance data file, we present data for the C5a cell line generated throughout the quality assessment process of the product. This data shows that the assays are reliable, accurate, and reproducible - and help keep errors resulting from biological variation and methodology at a minimum.

Performance Data

iLite® C5a Performance Data

The iLite C5a cells can be used for the quantification of C5a activity, and for the determination of inhibitory activity against either C5a itself or against the C5a receptor in test samples, including human serum.

In this performance data file, we present data for the C5a cell line generated throughout the quality assessment process of the product. This data shows that the assays are reliable, accurate, and reproducible - and help keep errors resulting from biological variation and methodology at a minimum.

LEARN MORE ABOUT

The most common bioanalytical aspects of the iLite C5a cell-based reporter gene assay

The cell-based iLite®  C5a assay is a cleverly designed, sensitive, and specific reporter-gene assay with firefly luciferase readout intended to be used in various applications throughout the drug development continuum.

The assay allows an easy, rapid, and accurate test format for a wide range of applications – including the determination of neutralizing antibodies against C5a and the quantification of C5a.

Included chapters:

  • Cell line Characterization
    - Validation of manufacturing process & determination of the overall cell line variation
    - Real-time stability study
    - Dynamic range assay application example
    - Plate homogeneity
  • Bioassay variation & performance
    - Accuracy & variations – day-to-day
    - Accuracy & variations – lot-to-lot
    - Linearity (parallelism) functional / linearity (parallelism) inhibitory
  • Cell line bioassay pre-clinical & clinical applications
    - Immunogenicity characterization


Complete the form to receive the Performance data via email!

Book a free consultation with one of our experts to discuss your specific needs!

Our scientific experts are here and ready to help - a great opportunity to discuss your specific projects!

Book a free iLite consultation