Performance Data

iLite® IL-6 Performance Data

iLite IL-6 Assay Ready Cells is a genetically engineered reporter gene cell line, optimized to respond to IL-6 with proportional expression of Firefly Luciferase where the activity of IL-6 and its agonist and antagonist can be assayed in a functional and biologically relevant format.

In this performance data file, we present data for the IL-6 cell line generated throughout the quality assessment process of the product. This data shows that the assays are reliable, accurate, and reproducible - and helps keep errors resulting from biological variation and methodology at a minimum.

Performance Data

iLite® IL-6 Performance Data

iLite IL-6 Assay Ready Cells is a genetically engineered reporter gene cell line, optimized to respond to IL-6 with proportional expression of Firefly Luciferase where the activity of IL-6 and its agonist and antagonist can be assayed in a functional and biologically relevant format.

In this performance data file, we present data for the IL-6 cell line generated throughout the quality assessment process of the product. This data shows that the assays are reliable, accurate, and reproducible - and helps keep errors resulting from biological variation and methodology at a minimum.

LEARN MORE ABOUT

The most common bioanalytical aspects of the iLite IL-6 cell-based reporter gene assay

The cell-based iLite®  IL-6 assay is a cleverly designed, sensitive, and specific reporter-gene assay with firefly luciferase readout intended to be used in various applications throughout the drug development continuum

The assay allows an easy, rapid, and accurate test format for a wide range of applications – including the determination of neutralizing antibodies against IL-6 and the quantification of IL-6.

Included chapters:

  • Cell line Characterization
    - Validation of manufacturing process & determination of the overall cell line variation
    - Real-time stability study
    - Dynamic range assay application example
    - Plate homogeneity
  • Bioassay variation & performance
    - Accuracy & variations – day-to-day
    - Accuracy & variations – lot-to-lot
    - Linearity (parallelism) functional / linearity (parallelism) inhibitory
  • Cell line bioassay pre-clinical & clinical applications
    - Immunogenicity characterization


Complete the form to receive the Performance data via email!

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We are currently looking for new users to try our iLite cell-based reporter gene assays. Find out how they can help in your bioassay and analytical work packages

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