Measuring the functional activity of TNF-α, the assay can be used for both potency and immunogenicity assessments of TNF-α inhibitors in the same assay. As such, the iLite TNF-α Assay Ready Cells also provide a means of directly comparing a biosimilar and innovator product in the same assay.
In this performance data file, we present data for the TNF-α cell line generated throughout the quality assessment process of the product. This data shows that the assays are reliable, accurate, and reproducible - and helps keep errors resulting from biological variation and methodology at a minimum.
Measuring the functional activity of TNF-α, the assay can be used for both potency and immunogenicity assessments of TNF-α inhibitors in the same assay. As such, the iLite TNF-α Assay Ready Cells also provide a means of directly comparing a biosimilar and innovator product in the same assay.
In this performance data file, we present data for the TNF-α cell line generated throughout the quality assessment process of the product. This data shows that the assays are reliable, accurate, and reproducible - and helps keep errors resulting from biological variation and methodology at a minimum.
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The cell-based iLite® TNF-α assay is a cleverly designed, sensitive, and specific reporter-gene assay with firefly luciferase readout intended to be used in various applications throughout the drug development continuum.
The assay allows an easy, rapid, and accurate test format for a wide range of applications – including the determination of neutralizing antibodies against TNF-α and the quantification of TNF-α.
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