Svar Life Science

July 3, 2025

Bridging Analytical Power: Integrating LC-MS and Ligand Binding Assays for Modern Bioanalysis

In the ever-evolving landscape of life sciences, innovation is the key to progress. That's why we're excited to spotlight the latest feature on SelectScience, Advances in Bioanalytical Method Development - a comprehensive resource for scientists and lab professionals seeking to enhance their analytical workflows and stay ahead of the curve.

This feature delves into the latest strategies for optimizing sample preparation and LC-MS acquisition, offering practical insights into improving sensitivity, selectivity, and overall method performance. From addressing common challenges in bioanalysis to supporting the development of next-generation therapeutics like oligonucleotides, bispecific antibodies, and ADCs, the spotlight brings together expert perspectives and real-world solutions.

 

July 3, 2025

Bridging Analytical Power: Integrating LC-MS and Ligand Binding Assays for Modern Bioanalysis

In the ever-evolving landscape of life sciences, innovation is the key to progress. That's why we're excited to spotlight the latest feature on SelectScience, Advances in Bioanalytical Method Development - a comprehensive resource for scientists and lab professionals seeking to enhance their analytical workflows and stay ahead of the curve.

This feature delves into the latest strategies for optimizing sample preparation and LC-MS acquisition, offering practical insights into improving sensitivity, selectivity, and overall method performance. From addressing common challenges in bioanalysis to supporting the development of next-generation therapeutics like oligonucleotides, bispecific antibodies, and ADCs, the spotlight brings together expert perspectives and real-world solutions.

 

Our Role in Advancing Integrated Analytical Strategies:

Bridging Analytical Power with Lablytica

As part of this feature, we're proud to share our collaborative editorial article with Lablytica Life Science, titled “Integrating LC-MS and ligand binding assays to meet bioanalytical demands”. In this piece, we explore how combining the strengths of liquid chromatography-mass spectrometry (LC-MS) with ligand binding assays (LBAs) is transforming the way we approach complex bioanalytical challenges.

This hybrid approach leverages the high specificity of LBAs with the structural insight and quantitative precision of LC-MS, offering a powerful toolkit for analyzing complex biological matrices. Our article highlights how this integration:

  • Enhances sensitivity and expands dynamic range
  • Supports regulatory compliance in biologics and oligonucleotide development
  • Enables more robust workflows from early discovery through clinical trials

Collaborating for Better Bioanalysis

By sharing our experience and insights, we aim to support the scientific community in adopting more versatile and effective bioanalytical strategies.

Whether you're navigating early-stage discovery or late-phase clinical trials, this article provides valuable insights into optimizing your bioanalytical workflows.