GAIN A COMPREHENSIVE UNDERSTANDING OF AAV IMMUNOGENICITY ASPECTS Join our upcoming webcast presented by Nature Research Custom Media to learn: Important aspects of AAV efficacy and potency The significance, potential impact, and evaluation methods of the pre-existing humoral immune response to AAV ... Read more
In the rapidly expanding field of gene therapy, ensuring safety and efficacy remains a primary challenge. Neutralizing antibodies (NAb) against adeno-associated virus (AAV) capsids can impede the success of treatments. This blog post explores strategies to overcome NAb challenges and introduces the ... Read more
Learn more about the process at Svar of designing, constructing, producing and validating a fit-for purpose potency assay for use in batch release of an AAV based gene therapy drug. In the Select Science editorial special feature "Advances in Drug Discovery", we describe the process of developing ... Read more
The right cell-based assay expertise can provide a clearer picture of what is actually occurring in the body. With the use of living cells, cell-based assays are able to produce more biologically relevant results, which is key to understanding a biotherapeutic. Although the use of living cells adds ... Read more
