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In the rapidly advancing field of gene therapy, adeno-associated viruses (AAV)stand out as powerful tools with immense potential. These vectors offer a precise means of delivering genetic material. However, ensuring their effectiveness and safety requires careful consideration of immunogenicity. To ... Read more
In the dynamic field of gene therapy, understanding the complexities of Adeno-Associated virus (AAV) immunogenicity is crucial for achieving success. Managing pre-existing neutralizing antibodies (NAbs) and Total Antibodies (TAbs) toward AAV capsids poses a significant challenge, potentially ... Read more
GAIN A COMPREHENSIVE UNDERSTANDING OF AAV IMMUNOGENICITY ASPECTS Join our upcoming webcast presented by Nature Research Custom Media to learn: Important aspects of AAV efficacy and potency The significance, potential impact, and evaluation methods of the pre-existing humoral immune response to AAV ... Read more
In the rapidly expanding field of gene therapy, ensuring safety and efficacy remains a primary challenge. Neutralizing antibodies (NAb) against adeno-associated virus (AAV) capsids can impede the success of treatments. This blog post explores strategies to overcome NAb challenges and introduces the ... Read more