WIESLAB® Complement System Screen - IVD

COMPL300

Gain a comprehensive picture of complement integrity or dysfunction across all three pathways with this functional screening ELISA, ideal for initial complement functional assessment and more extensive complement system profiling in clinical diagnostics.

Reliable, objective, and easy-to-interpret results
Results in just a few hours
Robust assay performance with low variability between users
Developed by our in-house experts in collaboration with key opinion leaders
Ready-to-use reagents for a streamlined workflow
High diagnostic sensitivity and specificity, ensuring accurate identification of complement deficiencies

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Product Overview

The WIESLAB® Complement System Screen kit is an immunoassay for the qualitative determination of complement function in human serum. The assay provides a comprehensive assessment of pathway specific complement function for the classical, MBL, and alternative complement pathways.

The Wieslab Complement assays combine the specific activation of each respective pathway with the use of labeled antibodies specific for TCC (C5b-9), detecting a neoepitope of the Terminal Complement Complex, produced as a result of complement activation. The amount of detected TCC is proportional to the functional activity of the complement pathway. By specifically only detecting de novo generated TCC, the assay provides qualitative results demonstrating if the complement pathways are preserved or deficient.

This product is also available as research use only - Product code: COMPL300RUO.

What's in the box?

One frame with break apart wells (4x8x3) - 4 strips for classical pathway (CP), 4 strips for MBL pathway (MP), 4 strips for alternative pathway (AP)
10 ml Diluent CP
10 ml Diluent MP
10 ml Diluent AP
13 ml Conjugate
13 ml Substrate solution
30 ml Wash solution 30x concentrated
0,2 ml Negative control (NC) containing human serum
0,2 ml Positive control (PC) containing freeze dried human serum

Plase note! All reagents in the kit are ready for use except washing solution and controls. The reagents should be stored at 2-8° C except the positive control. The positive control should be stored at -20° C.