The Wieslab® Complement system Screen kit is an enzyme immunoassay for the qualitative determination of functional classical, MBL and alternative complement pathways determination and determination of complement deficiencies in human serum. Non-human primate and swine samples can also be assayed with Wieslab® Complement system Screen.
The assay combines the specific activation of each pathway with the use of labeled antibodies specific for a neoepitope of the terminal complement complex, C5b-9, produced as the result of complement activation. The amount of C5b-9 generated is proportional to the functional activity of complement pathways.
The Wieslab Complement assays has been published as a useful tool in evaluation of complement therapeutics, in clinic, clinical trials and in drug development.
FOR RESEARCH USE ONLY
This product is also available for in vitro diagnostic use - Product code: COMPL CP300
|Read-out of results||Qualitative, Semi-quantitative,|
|Detection system||ALP/pNPP read at 405 nm|
|Regulatory status||Research Use Only|
Plase note! All reagents in the kit are ready for use except washing solution and controls. The reagents should be stored at 2-8° C except the positive control. The positive control should be stored at -20° C.
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