The Wieslab® Complement system Screen kit is an enzyme immunoassay for the qualitative determination of functional classical, MBL, and alternative complement pathways determination and determination of complement deficiencies in human serum. Non-human primate and swine samples can also be assayed with the Wieslab® Complement system Screen.
The assay combines the specific activation of each pathway with the use of labeled antibodies specific for a neoepitope of the terminal complement complex, C5b-9, produced as the result of complement activation. The amount of C5b-9 generated is proportional to the functional activity of complement pathways.
The Wieslab Complement assays have been published as a useful tool in the evaluation of complement therapeutics, in the clinic, clinical trials, and in drug development.
FOR RESEARCH USE ONLY
This product is also available for in vitro diagnostic use - Product code: COMPL300
|Read-out of results||Qualitative, Semi-quantitative,|
|Detection system||ALP/pNPP read at 405 nm|
|Regulatory status||Research Use Only|
Plase note! All reagents in the kit are ready for use except washing solution and controls. The reagents should be stored at 2-8° C except the positive control. The positive control should be stored at -20° C.
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