WIESLAB® Complement Classical Pathway (RUO)


The Wieslab® Complement System Classical Pathway is an enzyme immunoassay for the qualitative and/or semi-quantitative determination of functional classical complement pathway and determination of complement deficiencies in human serum. Non-human primate and swine samples can also be assayed with Wieslab® Complement System Classical Pathway.

The Wieslab Complement System Classical Pathway assay combines the specific activation of the pathway with the use of labeled antibodies specific for a neoepitope of the terminal complement complex, C5b-9, produced as the result of complement activation. The amount of complement activation can be expressed either in a qualitative way relative the value of a positive control or in a semi-quantitative way using a calibrator curve derived from a separate lyophilized activity control. 

The  Wieslab Complement assays have been published as useful tools in evaluation of complement therapeutics, in clinic, clinical trials and in drug development.


This product is also available for in vitro diagnostic use - Product code: COMPL CP310

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WIESLAB®  Complement System Classical Pathway - RUO
WIESLAB®  Complement System Classical Pathway - RUO

At a glance

Product code COMPLCP310RUO
Size 96 wells
Technology ELISA
Read-out of results Qualitative, Semi-quantitative,
Assay time 2h
Detection system ALP/pNPP read at 405 nm
Regulatory status Research Use Only

What's in the box?

  • One frame with break-apart wells (12x8)
  • 2 x 35 mL Diluent CP
  • 13 mL Conjugate
  • 13 mL Substrate solution
  • 30 mL Wash solution 30x concentrated
  • 0,2 mL Negative control (NC) containing human serum
  • Lyophilized positive control (PC) containing human serum
  • Lyophilized activity control (AC) for semi-quantitative application, containing human serum

Please note: All reagents in the kit are ready to use except wash solution and controls. The reagents should be stored at 2-8° C. The positive control and the activity control should be stored at -20° C upon arrival. The reconstituted positive control and activity control should be stored at –70° C and may be thawed once.


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