ONCOLOGY & IMMUNO-ONCOLOGY 

- the study & development of treatments that take advantage of the body's immune system to fight cancer

WIESLAB BIOANALYTICAL SERVICES

ONCOLOGY & IMMUNO-ONCOLOGY

There are numerous drug development projects that aim to transform scientific innovation into practice-changing cancer drugs. We can help accelerate the development of innovative, effective and cost-efficient oncology drugs and deliver them to patients as quickly as possible.

Let us help accelerate your small peptide drug development project!

Contact us to discuss your project with our scientists today! 

Contact Us

IMMUNO-ONCOLOGY AND ANTIBODY BASED THERAPIES

Immuno-oncology is a type of immunotherapy that is specifically targeted to use the body’s natural defenses (immune system) to fight cancer. 

The first immuno-oncology treatment was approved in 2010, and since then it has proven to be an effective treatment for melanoma and lymphoma, as well as lung, kidney and bladder cancer. By stimulating the immune system, the body is able to fight back, and destroy cancer cells while leaving the rest of the body unharmed.

The type of therapeutics defined as immuno-oncology drugs include, but are not limited to, monoclonal antibodies, bi-specific antibodies, antibody-drug-conjugates (ADC) and often include combination therapies. Therapies may often have an agonistic effect as well as stimulation and effector function.

YOUR CHALLENGES 

Testing your oncology therapies in systems that reflect the disease seen in humans

Common challenges when developing Immuno-Oncology related theraputics:

  • Bioanalytical assay strategies
  • General mitigations for Bioanalytical programs
  • Analytical risk assessments
  • How to select the right platform for Biomarker testing
  • Design of a tiered approach for immunogenicity testing
  • Special considerations for combination therapies

OUR EXPERINCE 
We know how to navigate the challenges of oncology drug development

Our team of Bioanalytical experts have worked with several oncology projects and faced many of the challenges that can occur in these complex projects. This includes assay development of PK and ADA assays, as well as assays to measure target protein and relevant biomarkers. We have the experience of using multi-plex panels with inflammatory biomarkers and will tailor the validation of the assays so that they that are fit for purpose in the context of use.

Whether you want to test your therapy in a cell biology assay consisting of the elements of the tumor microenvironment, or in models using real patient tissue, we are here to help!

WHERE WE CAN HELP 

Uncovering the future of cancer therapy

We offer service and expert knowledge within the following application areas: