Accelerating workflows for Calprotectin and Complement (C4d, TCC) biomarker assays with nanoliter-scale, microfluidic immunoassays

Listen to the on-demand webinar originally presented at the SelectScience Virtual Biopharmaceutical Summit 2020 by Ali Qamar, Product Manager at Svar Life Science.

This webinar is a collaboration between Svar Life Science & Gyros Technologies on "Accelerating workflows for calprotectin and complement (C4d, TCC) biomarker assays with nanoliter-scale, microfluidic immunoassays".

Key Learning Objectives 

  • Understand the disease states where monitoring of C4d, TCC, and calprotectin are utilized 
  • Learn about the advantages of microfluidic, nanoliter-scale automated immunoassays for biomarker analysis  
  • Understand assay performance and advantages over ELISA for the C4d, TCC, and calprotectin Gyrolab immunoassays  

Who Should Attend  

  • Scientists involved in drug development for autoimmune and infectious diseases or inflammatory diseases in academics, biotech, or pharma settings  
  • Researchers utilizing biomarker immunoassays on human clinical samples 
  • Bioanalytical groups in pharma or contract research organizations (CROs)

Svar Flexi Solutions - for automated platforms of your choice

Together with Gyros Protein Technologies, Svar Life Science has developed automated immunoassay for the specific detection of Complement C4d & TCC and Calprotectin in EDTA plasma samples using commercially available reagents.

Biomarker analysis is an important component of drug development and basic research to evaluate the safety and efficacy of a potential treatment. Automation of biomarker assays that allows reduced sample requirements and reagent consumption as well as optimization of workflows to bring productivity gains is highly desirable. Automated immunoassays for specific detection of complement analytes C4d and TCC, and calprotectin, an inflammatory bowel disease biomarker, have been developed using Svar Life Science Flexi reagents based on proprietary antibodies and Gyrolab® automated platforms.

The automated nanoliter-scale immunoassays enable users to independently set up, customize and optimize high performance nanoliter-scale sandwich immunoassays for determination and detection of complement C4d and TCC, as well as calprotectin in EDTA plasma and/or fecal extracts samples. Data on the assay working ranges, precision, linearity and spike recovery are presented for the three immunoassays.