Svar Life Science

June 17, 2022

Editorial Article: Novel COVID-19 biomarkers – The role of complement C4d & calprotectin

In this Editorial Article, Dr. Marie-Agnès Dragon-Durey highlights the role of complement C4d and calprotectin in the detection, diagnosis, and treatment of viral infectious diseases.

The complement system is an important part of the innate immune response and plays a key role in the defense against invading pathogens, including viruses, bacteria, fungi, and parasites. Recent studies have shown that complement overactivation plays a critical role in the pathogenesis of COVID-19 and other viral diseases, suggesting its huge potential as a biomarker for infectious diseases. 

June 17, 2022

Editorial Article: Novel COVID-19 biomarkers – The role of complement C4d & calprotectin

In this Editorial Article, Dr. Marie-Agnès Dragon-Durey highlights the role of complement C4d and calprotectin in the detection, diagnosis, and treatment of viral infectious diseases.

The complement system is an important part of the innate immune response and plays a key role in the defense against invading pathogens, including viruses, bacteria, fungi, and parasites. Recent studies have shown that complement overactivation plays a critical role in the pathogenesis of COVID-19 and other viral diseases, suggesting its huge potential as a biomarker for infectious diseases. 

The Complement System
Playing a key role in COVID-19

To find out more about the role of the complement system in viral infectious diseases, such as COVID-19, Select Science spoke with Dr. Marie-Agnès Dragon-Durey, associate professor in Immunology at the Université de Paris.

With over 20 years of experience improving diagnostics for autoimmune diseases and exploring the complement system, Dragon-Durey’s current research focuses on the use of biomarker assays to determine whether deficiencies, overactivation, or dysregulation in the complement system are causing or contributing to a person's disease or condition. Dragon-Durey has carried out work on the C4d protein using biomarker assays produced by Svar Life Science. We also have our own Calprotectin portfolio through our subsidiary Calpro.


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OUR COMPLEMENT AND CALPROTECTIN SOLUTIONS


Complement System Solutions

We offer functional and biomarker assays that can be used to explore every angle of complement system-involvement in a wide range of application areas. > Learn more


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Calpro is a world-leading provider of Calprotectin tests. Our aim is to provide solutions that are effective and user-friendly for the user without compromising the quality of the products. > Learn more