Svar Life Science

August 6, 2025

Take advantage of a more comprehensive way of looking at AAV Immunogenicity – With a Partner Who Gets the full picture

In gene therapy, immunogenicity isn't just a hurdle, it's a make-or-break factor!

Whether you are in the early or late stages of development, reliable data specific to your vector is essential to ensure relevance in your vector’s safety profile assessment.

Assessing the presence of anti-AAV antibodies and their neutralizing and toxicity capacity can also be essential. That´s where our AAV Safety Trifecta comes in!

 

August 6, 2025

Take advantage of a more comprehensive way of looking at AAV Immunogenicity – With a Partner Who Gets the full picture

In gene therapy, immunogenicity isn't just a hurdle, it's a make-or-break factor!

Whether you are in the early or late stages of development, reliable data specific to your vector is essential to ensure relevance in your vector’s safety profile assessment.

Assessing the presence of anti-AAV antibodies and their neutralizing and toxicity capacity can also be essential. That´s where our AAV Safety Trifecta comes in!

 

Assays That Answer Real-World Questions 

Our full AAV immunogenicity safety platform is built to give you a more comprehensive picture of your AAV vector, looking at it from many different angles:

  • Identify potential interfering total antibodies towards your AAV vector with TAb and
  • Asses Neutralizing antibodies with a cell based NAb assays for key AAV serotypes
  • Get a deep look into the safety profile by identifying Complement Activation in subject samples upon contact with the AAV capsids
  • Gain deeper understanding with our TAb and Complement Activation assays
  • Unique Custom assay development for novel or engineered vectors
  • Regulatory-aligned method development, sample analysis and reporting

Built Around Your Workflow 

No two programs are alike. That's why we offer:

  • Off-the-shelf assays for speed and simplicity
  • Custom assay development for unique constructs
  • Full CRO services from design to data

On-demand support when you need to scale or pivot

Whether you're a gene therapy company, a CRO expanding your capabilities, or an academic lab exploring new serotypes, we're here to help you move forward with confidence.

Why Svar Life Science?

Because we're more than a service provider - we're a strategic partner.

  • Scientific depth: We understand the biology behind your vector
  • Operational agility: We adapt to your needs, not the other way around
  • Regulatory insight: We help you stay ahead of evolving expectations
  • Proven reliability: You get results you can trust, timelines you can count on

 

Let's take the guesswork out of immunogenicity testing.

Whether you're preparing for IND submission or exploring a novel AAV construct, we're ready to support your next milestone.
Schedule a consultation with our team